Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353629 | 0.99 | LMNA (0.43) | LMNAKDM4EALDH1A1TDP1DRD4 | |
| SCHEMBL8355265 | 0.80 | LMNA (0.60) | LMNAALDH1A1DRD4KMT2APOLB | |
| SCHEMBL8354585 | 0.79 | LMNA (0.61) | LMNAALDH1A1DRD4KMT2APOLB | |
| SCHEMBL25668894 | 0.78 | ALDH1A1 (0.46) | LMNAKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL3148838 | 0.76 | DRD4 (0.48) | LMNAALDH1A1DRD4KMT2AMEN1 | |
| SCHEMBL8353849 | 0.76 | HDAC1 (0.39) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3577293 | 0.76 | DRD4 (0.64) | LMNAKDM4EALDH1A1TDP1DRD4 | |
| SCHEMBL17976036 | 0.75 | OPRK1 (0.48) | ALDH1A1DRD4POLBHTTGLA | |
| SCHEMBL13369346 | 0.75 | KMT2A (0.39) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3158672 | 0.75 | DRD4 (0.49) | LMNAALDH1A1DRD4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048081-A2 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |