Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505235 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8505238 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8354878 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8504934 | 0.81 | GPR119 (0.53) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8504930 | 0.81 | GPR119 (0.53) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8354977 | 0.81 | ITGB3 (0.45) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8354618 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8351846 | 0.80 | ITGB3 (0.47) | SMN1; SMN2MAPTKDM4EGFERALDH1A1 | |
| SCHEMBL8348648 | 0.79 | ITGB3 (0.52) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 | |
| SCHEMBL8352179 | 0.79 | STS (0.50) | SMN1; SMN2LMNAMAPTMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |