Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352179 | 0.90 | STS (0.50) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL7658148 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BSMN1; SMN2LMNAMAPT | |
| SCHEMBL8354977 | 0.84 | ITGB3 (0.45) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL383058 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL8348900 | 0.80 | SMN1; SMN2 (0.47) | ITGB3ITGA2BKDM4EPKMSMN1; SMN2 | |
| SCHEMBL8354878 | 0.80 | SMN1; SMN2 (0.59) | KDM4EPKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL8348629 | 0.80 | SMN1; SMN2 (0.53) | KDM4EPKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL8355408 | 0.79 | SMN1; SMN2 (0.46) | KDM4EPKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL8354618 | 0.79 | SMN1; SMN2 (0.45) | KDM4EPKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL8352940 | 0.79 | ITGB3 (0.79) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |