Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358874 | 0.97 | KMT2A (0.59) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9168640 | 0.84 | KMT2A (0.74) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8578047 | 0.83 | ADORA1 (0.47) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL9170314 | 0.80 | ADORA1 (0.47) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8579759 | 0.80 | KMT2A (0.56) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL6154374 | 0.78 | ADORA2B (0.43) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8577929 | 0.73 | KMT2A (0.70) | KMT2AMEN1POLBRAB9AALDH1A1 | |
| SCHEMBL8606081 | 0.72 | KMT2A (0.66) | KMT2AADORA3MEN1POLBRAB9A | |
| SCHEMBL8358348 | 0.72 | ADORA1 (0.46) | KMT2AADORA3ADORA1ADORA2BADORA2A | |
| SCHEMBL8577877 | 0.72 | ADORA2B (0.60) | KMT2AADORA3ADORA1ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031101-A1 | ADENOSINE RECEPTOR ANTAGONISTS WITH IMPROVED BIOACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 1999-06-24 | — | — | WO | disclosed |