Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281753 | 1.00 | ELANE (0.49) | ELANENPC1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL8284648 | 0.90 | FKBP1A (0.48) | ELANENPC1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL16316575 | 0.85 | SMN1; SMN2 (0.53) | ELANENPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL8283586 | 0.81 | MEN1 (0.44) | ELANENPC1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL5740609 | 0.80 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL29302842 | 0.80 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL29302825 | 0.80 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL820518 | 0.80 | SMN1; SMN2 (0.58) | ELANENPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL818735 | 0.80 | SMN1; SMN2 (0.58) | ELANENPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL21874593 | 0.80 | SMN1; SMN2 (0.58) | ELANENPC1RAB9ASMN1; SMN2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062265-A2 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |