Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150505 | 0.82 | MEN1 (0.67) | NPC1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL19575701 | 0.81 | NPC1 (0.52) | NPC1MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL2795484 | 0.81 | KCNMA1 (0.65) | NPC1MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL27775431 | 0.81 | GRIK1 (0.53) | NPC1MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL1437258 | 0.79 | MAPT (0.63) | NPC1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30274478 | 0.78 | NPC1 (0.61) | NPC1ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL4799616 | 0.78 | NPC1 (0.61) | NPC1ALDH1A1KDM4EGAARAB9A | |
| SCHEMBL7255416 | 0.78 | GRIK1 (0.67) | MEN1KMT2AALDH1A1KDM4EGRIK1 | |
| SCHEMBL27672011 | 0.77 | CXCR2 (0.59) | NPC1MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL10522333 | 0.76 | NPC1 (0.50) | NPC1MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |