Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295570 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BHDAC8DPP4DPP8 | |
| SCHEMBL7295577 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BHDAC8DPP4DPP8 | |
| SCHEMBL7295572 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BHDAC8DPP4DPP8 | |
| SCHEMBL8548212 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BDPP4DPP8DPP7 | |
| SCHEMBL8548220 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BDPP4DPP8DPP7 | |
| SCHEMBL7287954 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BHDAC8P2RX7CTSL | |
| SCHEMBL7287967 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BHDAC8P2RX7CTSL | |
| SCHEMBL7287962 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BHDAC8P2RX7CTSL | |
| SCHEMBL7284866 | 0.76 | P2RX7 (0.44) | ITGB3ITGA2BHDAC8P2RX7CTSL | |
| SCHEMBL7284869 | 0.76 | P2RX7 (0.44) | ITGB3ITGA2BHDAC8P2RX7CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935963-A | (4-GUANIDINOBENZOYLAMINO)ACETYL-3-(3-(4-GUANIDINOBENZOYLAMINO) PROPYL)-2-OXOPIPERAZINE-1-ACETIC ACID OR A SALT; CONTROLLING OR INHIBITING CELL-ADHESION; PLATELET ANTIAGGREGATION WITHOUT LONG HEMORRHAGING; ANTIICHEMIC AGENTS; ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5876756-A | SUSTAINED RELEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-02 | — | — | US | disclosed |