Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384226 | 0.89 | LMNA (0.46) | LMNAMAPTADORA2ASMN1; SMN2POLB | |
| SCHEMBL11193732 | 0.86 | HCRTR1 (0.39) | LMNAMAPTALOX12GRM5HCRTR1 | |
| SCHEMBL11210810 | 0.85 | LMNA (0.38) | LMNAMAPTALOX12GRM5HCRTR1 | |
| SCHEMBL8355713 | 0.84 | ALDH1A1 (0.37) | LMNAMAPTADORA2ASMN1; SMN2MEN1 | |
| SCHEMBL8355552 | 0.83 | DAO (0.40) | LMNAMAPTADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL8351882 | 0.82 | ALDH1A1 (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL8356048 | 0.81 | ALDH1A1 (0.34) | LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8355744 | 0.81 | ALDH1A1 (0.38) | LMNAMAPTALOX12SMN1; SMN2MEN1 | |
| SCHEMBL10958740 | 0.78 | L3MBTL1 (0.42) | LMNAALOX12GRM5MEN1HTT | |
| SCHEMBL11193702 | 0.77 | GRIN2D (0.34) | LMNAALOX12GRM5ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952361-A | Compositions | DIAS NAHOUM CESAR ROBERTO (US) | 1999-09-14 | — | — | US | disclosed |
| US-5908853-A | THERAPY FOR SEXUAL DISORDERS | Nahoum, Cesar Roberto Dias (BR) | 1999-06-01 | — | — | US | disclosed |
| US-5773457-A | Compositions | Nahoum, Cesar Roberto Dias (BR) | 1998-06-30 | — | — | US | disclosed |