Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058796 | 0.79 | ALDH1A1 (0.59) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL11530441 | 0.78 | DAO (0.38) | LMNATSHRSMN1; SMN2HRH4DAO | |
| SCHEMBL8355557 | 0.78 | PLAU (0.46) | LMNAMAPTPLAUDAO | |
| SCHEMBL30732408 | 0.77 | ALDH1A1 (0.58) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL12055882 | 0.77 | ALDH1A1 (0.58) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL11198686 | 0.77 | LMNA (0.49) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL7296244 | 0.76 | HRH1 (0.57) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL8409739 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL19305939 | 0.76 | ALDH1A1 (0.57) | LMNAALDH1A1CYP1A2TSHRMAPT | |
| SCHEMBL8351885 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1HRH4PLAUDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952361-A | Compositions | DIAS NAHOUM CESAR ROBERTO (US) | 1999-09-14 | — | — | US | disclosed |
| US-5908853-A | THERAPY FOR SEXUAL DISORDERS | Nahoum, Cesar Roberto Dias (BR) | 1999-06-01 | — | — | US | disclosed |
| US-5773457-A | Compositions | Nahoum, Cesar Roberto Dias (BR) | 1998-06-30 | — | — | US | disclosed |