Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11201133 | 0.98 | HRH1 (0.55) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| Bromide SCHEMBL10628485 | 0.98 | HRH1 (0.55) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL5169553 | 0.89 | HRH1 (0.56) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL31058796 | 0.88 | ALDH1A1 (0.59) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL30732408 | 0.86 | ALDH1A1 (0.58) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL12055882 | 0.86 | ALDH1A1 (0.58) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL6130015 | 0.83 | CYP1A2 (0.63) | HRH1CYP1A2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL11210347 | 0.83 | HRH1 (0.66) | HRH1CYP1A2ALDH1A1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL31146769 | 0.81 | HRH1 (0.63) | HRH1CYP1A2ALDH1A1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL17633755 | 0.81 | HRH1 (0.63) | HRH1CYP1A2ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488544-B1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | UNIV MONASH (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| WO-2011044637-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY (AU) | 2011-04-21 | — | — | WO | disclosed |
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| US-4145546-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |
| US-4140783-A | INHIBITORS OF HISTAMINE H-2 RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-02-20 | — | — | US | disclosed |
| US-4112104-A | UREA, THIOUREA OR GUANIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |
| US-4080459-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-03-21 | — | — | US | disclosed |
| US-4056620-A | INHIBITION OF HISTAMINE H-2 RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-11-01 | — | — | US | disclosed |
| US-4025527-A | H-2 HISTAMINE RECEPTOR INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-24 | — | — | US | disclosed |
| US-4024260-A | INHIBITS H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4013659-A | CERTAIN N,N'-DISUBSTITUTED GUANIDINE COMPOUNDS AND THEIR USE | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
| US-4013769-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
| US-4002671-A | REDUCE SEBUM SECRETION ON SCALP OR SKIN | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MAX, SPR, CCL2 | HRH1 1554/4885CYP1A2 3926/4885ALDH1A1 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.