Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.52 |
| ▸ | MAP2K4 | P45985 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | MAPK6 | Q16659 | 5/20 | 0.51 |
| ▸ | MAPKAPK3 | Q16644 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22753252 | 0.85 | MAP2K4 (0.47) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL2671620 | 0.84 | JAK2 (0.49) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL13387003 | 0.83 | YTHDC1 (0.61) | PRKAG1PRKAA1PRKAB1MAP2K4MAPK1 | |
| SCHEMBL117222 | 0.81 | JAK2 (0.64) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL18932046 | 0.81 | MAP2K4 (0.46) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL19641478 | 0.81 | PRKAG1 (0.53) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL18967793 | 0.80 | MAP2K4 (0.54) | PRKAG1PRKAA1PRKAB1MAP2K4MAPK1 | |
| SCHEMBL31504557 | 0.80 | MAP2K4 (0.57) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| SCHEMBL1145076 | 0.80 | MAP2K4 (0.57) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E | |
| Hydrochloric Acid SCHEMBL17206177 | 0.80 | JAK2 (0.62) | MAP2K4MAPK1MAPK6MAPKAPK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228513-A | — | — | None | — | — | JP | disclosed |
| JP-H11228513-A | 4-ACETYLAMINO-3-METHYLBENZOIC ACID COMPOUND, ITS PRODUCTION AND PRODUCTION OF 1H-INDAZOLE-5-CARBOXYLIC ACID USING THE SAME | SUMIKA FINE CHEMICALS CO LTD | 1999-08-24 | — | — | JP | disclosed |