Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158944 | 0.81 | MAOB (0.49) | F10HTTIDO1 | |
| SCHEMBL6158948 | 0.81 | MAOB (0.49) | F10HTTIDO1 | |
| SCHEMBL5892429 | 0.80 | BCAT2 (0.46) | HTTALDH1A1CYP2A6KMT2ARECQL | |
| SCHEMBL4986625 | 0.77 | HTT (0.41) | HTTALDH1A1CYP2A6KMT2A | |
| SCHEMBL4989279 | 0.76 | MAOB (0.40) | HTTALDH1A1CYP2A6KMT2A | |
| SCHEMBL4986583 | 0.73 | L3MBTL1 (0.41) | HTTALDH1A1KMT2A | |
| SCHEMBL4987610 | 0.72 | GAA (0.49) | KMT2ATSHR | |
| SCHEMBL7220251 | 0.72 | MAOB (0.46) | F3HTTIDO1ALDH1A1CYP2A6 | |
| SCHEMBL3338836 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CYP2A6KMT2ARECQLTAAR1 | |
| SCHEMBL9665775 | 0.71 | GAA (0.59) | IDO1ALDH1A1PRSS1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | claimed |
| WO-1999040882-A2 | STEREOSELECTIVE Tc-99m LIGANDS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-08-19 | — | — | WO | disclosed |