Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579087 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL6577356 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL865066 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL3959220 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL6577464 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL6577430 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL6577467 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL8357720 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL98284 | 1.00 | SIGMAR1 (0.57) | SIGMAR1MAPTRXFP1MAOAMAOB | |
| SCHEMBL96648 | 0.98 | SIGMAR1 (0.54) | SIGMAR1MAPTRXFP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998635-A | CATALYTIC CYCLIZATION AN ALDEHYDE WITH A KETENE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |