Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98284 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL865066 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL6577464 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL6577430 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL11049963 | 0.98 | SIGMAR1 (0.52) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL11049892 | 0.98 | SIGMAR1 (0.52) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL8357720 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL8357002 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL6577467 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL6577356 | 0.98 | SIGMAR1 (0.57) | SIGMAR1MAOAMAOBMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063666-B | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117188149-B | Method for durable flame-retardant antibacterial coating polyester fabric | 江苏恒力化纤股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117188149-A | Method for durable flame-retardant antibacterial coating polyester fabric | 江苏恒力化纤股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-109694350-B | Compound containing fluoromethyl and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-05-09 | — | — | CN | claimed |
| CN-116063666-A | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2023-05-05 | — | — | CN | claimed |
| CN-114075108-A | Deuteration of aldehyde and application in preparing deuteration aldehyde | 南开大学 | 2022-02-22 | — | — | CN | claimed |
| CN-113444005-A | Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin | 四川大学 | 2021-09-28 | — | — | CN | claimed |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | claimed |
| EP-3665163-A1 | USE OF AMBROCENIDE ® FOR INTENSIFYING A LILY OF THE VALLEY SCENT | Symrise AG (DE) | 2020-06-17 | — | — | EP | claimed |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | claimed |
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| WO-2008012227-A2 | PYRAZOLES AS GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-31 | — | — | WO | claimed |
| US-20080021032-A1 | Pyrazole glucokinase activators | BERTHEL STEVEN JOSEPH | 2008-01-24 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |
| US-6388081-B1 | 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries | LION BIOSCIENCE AG (DE) | 2002-05-14 | — | — | US | claimed |
| US-6262269-B1 | 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries | TREGA BIOSCIENCES, INC. | 2001-07-17 | — | — | US | claimed |
| EP-0977989-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-5554339-A | Process for the manufacture of wholly microfabricated biosensors | I-STAT CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| EP-0443559-A2 | HIV protease inhibiting agents | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | SIGMAR1 4878/4885MAOA 1516/4885MAOB 1282/4885 |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | PCSK9, PCSK7, PCSK6 | SIGMAR1 4878/4885MAOA 1516/4885MAOB 1282/4885 |
| US-20080021032-A1 | Pyrazole glucokinase activators | GCKR, GCK, GALK1 | SIGMAR1 4138/4885MAOA 3087/4885MAOB 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.