SCHEMBL98284

SCHEMBL98284

O=CCCCCCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.57
MAPT P10636 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.48
TRPV1 Q8NER1 1/20 0.47
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
ALOX5 P09917 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6579087 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL6577356 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL865066 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL3959220 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL6577464 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL6577430 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL6577467 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL8357720 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL8357002 1.00 SIGMAR1 (0.57) SIGMAR1MAPTRXFP1MAOAMAOB
SCHEMBL96648 0.98 SIGMAR1 (0.54) SIGMAR1MAPTRXFP1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3017000-B1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR ARKEMA FRANCE (FR) 2024-05-29 EP claimed
US-20160130419-A1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR ARKEMA FRANCE (FR) 2016-05-12 US claimed
EP-3017000-A1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR Arkema France (FR) 2016-05-11 EP claimed
WO-2015001234-A1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR ARKEMA FRANCE (FR) 2015-01-08 WO claimed
US-20250282818-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION,INCORPORATED (US) 2025-09-11 US disclosed
EP-3017000-B1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR ARKEMA FRANCE (FR) 2024-05-29 EP disclosed
WO-2023211883-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-02 WO disclosed
WO-2023211883-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-02 WO disclosed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
CN-112250557-A Method for efficiently synthesizing 1, 6-diene-3-ketone derivative 徐州工程学院 2021-01-22 CN disclosed
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-10626095-B2 Cyanotriazole compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-04-21 US disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
WO-1986001208-A1 STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF SRI INTERNATIONAL (US) 1986-02-27 WO disclosed
WO-1985005361-A1 17abeta-HYDROXY-7alpha-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES SRI INTERNATIONAL (US) 1985-12-05 WO disclosed
EP-0053017-B1 AMIDE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-20 EP disclosed
US-4487772-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO. LTD. (JP) 1984-12-11 US disclosed
EP-0126635-A2 Novel oxindole derivative OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-11-28 EP disclosed
US-4468402-A Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-08-28 US disclosed
US-4454130-A CARDIOTONIC, HYPOTENSIVE AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626095-B2 Cyanotriazole compounds CS, PC, ACAT1 SIGMAR1 4091/4885MAPT 2196/4885RXFP1 2555/4885
US-20250282818-A1 SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF PSMB10, PSMB1, PSMB5 SIGMAR1 4031/4885MAPT 2616/4885RXFP1 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.