Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184868 | 0.71 | ALDH1A1 (0.41) | HTTALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL6184874 | 0.71 | ALDH1A1 (0.41) | HTTALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL6184863 | 0.71 | ALDH1A1 (0.41) | HTTALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL315417 | 0.62 | ENPP2 (0.48) | ENPP2HTTALDH1A1POLBMAPT | |
| SCHEMBL14434007 | 0.58 | CYP1A2 (0.33) | — | |
| SCHEMBL5217057 | 0.57 | SMN1; SMN2 (0.52) | ENPP2ALDH1A1MAPTKDM4E | |
| SCHEMBL5006682 | 0.56 | MAPT (0.52) | HTTALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL8323521 | 0.56 | NPSR1 (0.31) | POLBKMT2A | |
| SCHEMBL315267 | 0.55 | MAPT (0.44) | ENPP2HTTALDH1A1POLBMAPT | |
| SCHEMBL4056759 | 0.55 | ALDH1A1 (0.46) | HTTALDH1A1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037809-A1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |