Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965960 | 0.83 | AOC3 (0.40) | AOC3GAARIPK1ALDH1A1KDM4E | |
| SCHEMBL14910072 | 0.78 | RIPK1 (0.43) | AOC3RIPK1ALDH1A1POLBLMNA | |
| SCHEMBL5065151 | 0.76 | KDM4E (0.55) | AOC3GAAALDH1A1KDM4ESLC6A4 | |
| SCHEMBL14908702 | 0.76 | KDM4E (0.55) | AOC3GAAALDH1A1KDM4ESLC6A4 | |
| SCHEMBL3005419 | 0.76 | AOC3 (0.51) | AOC3GAAALDH1A1KDM4EATM | |
| SCHEMBL5065158 | 0.76 | KDM4E (0.55) | AOC3GAAALDH1A1KDM4ESLC6A4 | |
| SCHEMBL1529959 | 0.76 | AOC3 (0.37) | AOC3GAAALDH1A1KDM4EATM | |
| SCHEMBL1529961 | 0.76 | AOC3 (0.37) | AOC3GAAALDH1A1KDM4EATM | |
| SCHEMBL19459927 | 0.74 | GAA (0.44) | AOC3GAAALDH1A1KDM4EPOLB | |
| SCHEMBL19517259 | 0.74 | GAA (0.44) | AOC3GAAALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143290-B2 | Chemical compounds 572 | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |
| US-20110071194-A1 | Chemical Compounds 572 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071194-A1 | Chemical Compounds 572 | ABCG2, ABCB1, CYP11B2 | AOC3 2843/4885GAA 215/4885RIPK1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.