Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.52 |
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | PLG | P00747 | 5/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 10/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353843 | 0.88 | F2 (0.43) | F2F10PLGTMPRSS6PRSS1 | |
| SCHEMBL8344650 | 0.88 | F2 (0.56) | F2F10PLGKLKB1PROC | |
| SCHEMBL8358388 | 0.81 | F2 (0.59) | F2F10PLGKLKB1PROC | |
| SCHEMBL8358318 | 0.80 | F2 (0.51) | F2F10PLGKLKB1PROC | |
| SCHEMBL8220846 | 0.80 | F2 (0.62) | F2F10PLGKLKB1PROC | |
| SCHEMBL17381408 | 0.79 | F2 (0.53) | F2F10PLGKLKB1PROC | |
| SCHEMBL8354790 | 0.78 | F2 (0.49) | F2F10PLGKLKB1PROC | |
| SCHEMBL8346530 | 0.78 | F2 (0.57) | F2F10PLGTMPRSS6PRSS1 | |
| SCHEMBL8345186 | 0.78 | F2 (0.51) | F2F10PLGKLKB1PROC | |
| SCHEMBL12156653 | 0.78 | F2 (0.61) | F2F10PLGKLKB1PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483285-B1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | disclosed |