SCHEMBL8358014

SCHEMBL8358014

COC(=O)CCCCC(=O)NCCCc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.71
LMNA P02545 4/20 0.63
KDM4E B2RXH2 1/20 0.63
TSHR P16473 1/20 0.62
HPGD P15428 2/20 0.60
GAA P10253 1/20 0.60
PKM P14618 1/20 0.59
HDAC3 O15379 3/20 0.58
HDAC1 Q13547 3/20 0.58
HDAC2 Q92769 3/20 0.58
HDAC10 Q969S8 3/20 0.58
HDAC11 Q96DB2 3/20 0.58
HDAC8 Q9BY41 3/20 0.58
HDAC6 Q9UBN7 3/20 0.58
NCOR2 Q9Y618 3/20 0.58
HDAC4 P56524 2/20 0.58
HDAC9 Q9UKV0 2/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
NAMPT P43490 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1232716 0.99 L3MBTL1 (0.69) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL1231698 0.94 LMNA (0.68) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL1233076 0.94 LMNA (0.63) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL1231729 0.91 HDAC3 (0.71) L3MBTL1LMNAKDM4EHPGDHDAC3
SCHEMBL1231469 0.90 LMNA (0.70) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL15560138 0.90 HDAC3 (0.70) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL1291537 0.88 L3MBTL1 (0.71) L3MBTL1LMNAKDM4ETSHRHPGD
SCHEMBL117432 0.86 MAPT (0.61) LMNAKDM4EHDAC3HDAC1HDAC2
SCHEMBL7201053 0.86 L3MBTL1 (0.89) L3MBTL1LMNATSHRHPGDGAA
SCHEMBL19438777 0.85 SIGMAR1 (0.59) L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO disclosed