Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GRK2 | P25098 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.54 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21968899 | 0.74 | FABP4 (1.00) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL16706086 | 0.74 | MEN1 (1.00) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12899541 | 0.58 | MAPT (0.41) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8358258 | 0.58 | NR4A1 (1.00) | MEN1KMT2APOLBL3MBTL1TDP1 | |
| SCHEMBL11303911 | 0.58 | MAPT (0.52) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL11297851 | 0.57 | MAPT (0.49) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL11297858 | 0.57 | MEN1 (0.49) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8328341 | 0.57 | MAPT (0.56) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8028472 | 0.57 | MAPT (0.51) | PTPN5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL2028311 | 0.56 | SLC6A2 (0.68) | MEN1KMT2APOLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039540-A2 | D-AMINO ACID OXIDASE INHIBITORS FOR LEARNING AND MEMORY | SEPRACOR INC. (US) | 2003-05-15 | — | — | WO | disclosed |