Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358688 | 0.86 | SLC1A2 (0.40) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6703472 | 0.81 | SLC1A2 (0.36) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5690924 | 0.78 | SLC1A2 (0.46) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8358427 | 0.78 | MEN1 (0.34) | TSHR | |
| Hydrochloric Acid SCHEMBL6703583 | 0.76 | GRM8 (0.41) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8354012 | 0.75 | SLC1A2 (0.42) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL23718843 | 0.75 | SLC1A2 (0.57) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6702822 | 0.74 | SLC1A2 (0.38) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6701165 | 0.72 | GRM8 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8532802 | 0.70 | SLC1A2 (0.44) | GRM8GRM6GRM2GRM3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045898-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |