Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 6/20 | 0.48 |
| ▸ | HTR2C | P28335 | 13/20 | 0.46 |
| ▸ | HTR2B | P41595 | 9/20 | 0.46 |
| ▸ | HTR2A | P28223 | 8/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781225 | 0.84 | NPC1 (0.50) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL8599856 | 0.81 | NPC1 (0.36) | PPOXHTR2CHTR2BGAA | |
| SCHEMBL8599861 | 0.81 | NPC1 (0.36) | PPOXHTR2CHTR2BGAA | |
| SCHEMBL8601896 | 0.81 | NPC1 (0.36) | PPOXHTR2CHTR2BGAA | |
| SCHEMBL7887159 | 0.80 | HTR2C (0.41) | PPOXHTR2CHTR2BHTR2AADRB2 | |
| SCHEMBL8177207 | 0.80 | PPOX (0.45) | PPOXHTR2CHTR2BHTR2AADRB2 | |
| SCHEMBL6408609 | 0.80 | ADRA2A (0.40) | PPOXADRA2AADRA2BADRA2CGAA | |
| SCHEMBL30826270 | 0.79 | HTR2C (0.48) | PPOXHTR2CHTR2BHTR2AADRB2 | |
| SCHEMBL9873406 | 0.78 | PPOX (0.44) | PPOXHTR2CHTR2BHTR2AADRB2 | |
| SCHEMBL9873396 | 0.78 | NPC1 (0.36) | PPOXGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200924-B | 4-amino-5-pyrimidine formamide compound and preparation method and application thereof | 南开大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-113200924-A | 4-amino-5-pyrimidine formamide compound and preparation method and application thereof | 南开大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-113200985-A | Pteridinone compound and preparation method and application thereof | 南开大学 | 2021-08-03 | — | — | CN | disclosed |
| EP-0763011-B1 | PROCESS FOR THE PREPARATION OF UNSATURATED AMINO COMPOUNDS | NOVARTIS AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| US-5856578-A | CATALYTIC HYDROGENATION OF THE CORRESPONDING AROMATIC NITRO COMPOUND IN PRESENCE OF NOBLE METAL CATALYST | NORVARTIS CORPORATION (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0763011-A1 | PROCESS FOR THE PREPARATION OF UNSATURATED AMINO COMPOUNDS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5068365-A | Herbicides | TOSOH CORPORATION (JP) | 1991-11-26 | — | — | US | disclosed |
| US-5053071-A | For cereal crops | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4948418-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES; WEED CONTROL, RICE, WHEAT, BARLEY, CORN, SOYBEANS, BEETS AND COTTON | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4881967-A | Heterocyclic 2,3-dihydrobenzofuran herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0326764-A2 | Hexahydrophthalic anilide derivatives and herbicide compositions containing the same | Tosoh Corporation (JP) | 1989-08-09 | — | — | EP | disclosed |
| EP-0271170-A2 | Herbicidal substituted benzofurans and benzopyrans | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | disclosed |