Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215967 | 0.78 | GAA (0.39) | HTR2CHTR2BHTR2AADRA2AADRA2B | |
| SCHEMBL29745376 | 0.78 | GAA (0.39) | HTR2CHTR2BHTR2AADRA2AADRA2B | |
| SCHEMBL8177207 | 0.78 | PPOX (0.45) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL8358490 | 0.78 | PPOX (0.48) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL30826270 | 0.76 | HTR2C (0.48) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL10399423 | 0.74 | HTR2C (0.51) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL30826232 | 0.74 | HTR2C (0.51) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL4236099 | 0.73 | ADRA2A (0.40) | HTR2CHTR2BHTR2AADRA2AADRA2B | |
| SCHEMBL8178290 | 0.73 | GAA (0.57) | PPOXHTR2CHTR2BGAATSHR | |
| SCHEMBL8186579 | 0.73 | GAA (0.47) | PPOXHTR2CHTR2BHTR2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007393-A1 | PESTICIDAL 3-ARYLURACIL ETHERS AND THIOETHERS | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-30 | — | — | WO | disclosed |