Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306614 | 0.67 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL20038209 | 0.67 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8286227 | 0.66 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20037520 | 0.66 | PIM1 (0.41) | SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL20037529 | 0.65 | SOS1 (0.35) | SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL13664821 | 0.65 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18291188 | 0.65 | TLR8 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6767507 | 0.64 | ALDH1A1 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20038317 | 0.64 | RECQL (0.37) | SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL1578400 | 0.64 | BPTF (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026652-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |