Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 3/20 | 0.49 |
| ▸ | IL1RN | P18510 | 3/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354794 | 1.00 | KDM4E (0.50) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL8360534 | 0.90 | ERAP2 (0.49) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL8422131 | 0.87 | MMP9 (0.52) | MEN1KMT2AIL1RNECE1ERAP2 | |
| SCHEMBL14446443 | 0.87 | GHSR (0.53) | IL1RNECE1ERAP2ERAP1ACE | |
| SCHEMBL14446363 | 0.87 | GHSR (0.53) | IL1RNECE1ERAP2ERAP1ACE | |
| SCHEMBL8418339 | 0.87 | MMP9 (0.52) | MEN1KMT2AIL1RNECE1ERAP2 | |
| SCHEMBL14446439 | 0.87 | GHSR (0.53) | IL1RNECE1ERAP2ERAP1ACE | |
| SCHEMBL14446366 | 0.87 | GHSR (0.53) | IL1RNECE1ERAP2ERAP1ACE | |
| SCHEMBL8196579 | 0.84 | MAPT (0.62) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL8196577 | 0.84 | MAPT (0.62) | KDM4EMEN1LMNAMPOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003017924-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |