SCHEMBL83591

SCHEMBL83591

CO[Si](CCCNC(=O)CNC(C)=O)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PAOX Q6QHF9 3/20 0.36
ADRA1A P35348 1/20 0.35
MTNR1A P48039 4/20 0.35
MTNR1B P49286 4/20 0.35
FAAH O00519 1/20 0.34
POLB P06746 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL960689 0.87 KDM4E (0.56) KDM4EMAPK1HIF1ATSHRPAOX
SCHEMBL28674810 0.83 TSHR (0.36) TSHRMEN1KMT2APOLB
SCHEMBL7556625 0.83 KDM4E (0.39) KDM4EMAPK1HIF1ATSHRMEN1
SCHEMBL18180992 0.83 TSHR (0.44) KDM4EMAPK1HIF1ATSHRMEN1
SCHEMBL9322077 0.81 TSHR (0.40) KDM4EMAPK1HIF1ATSHRMEN1
SCHEMBL22174072 0.81 TSHR (0.52) KDM4ETSHRMEN1KMT2AFAAH
SCHEMBL16422261 0.79 TSHR (0.41) TSHRMEN1KMT2AMTNR1AMTNR1B
SCHEMBL18164189 0.79 TSHR (0.55) TSHRMEN1KMT2AFAAHPOLB
SCHEMBL16477882 0.79 MEN1 (0.61) TSHRMEN1KMT2AMTNR1AMTNR1B
SCHEMBL14076038 0.79 TDP1 (0.47) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002894-A1 BIOCATALYTICAL COMPOSITIONS INOFEA AG (CH) 2025-01-02 US claimed
EP-4433548-A1 BIOCATALYTICAL COMPOSITIONS Inofea AG (CH) 2024-09-25 EP claimed
WO-2023089035-A1 BIOCATALYTICAL COMPOSITIONS INOFEA AG (CH) 2023-05-25 WO claimed
US-9879362-B2 Method for producing nanofibers capable of storing and transferring nitric oxide and nanofibers capable of storing and transferring nitric oxide produced thereby I-SENS, INC. (KR) 2018-01-30 US claimed
US-9840639-B2 Hydrophilic anti-fog coatings INNOSENSE LLC (US) 2017-12-12 US claimed
EP-3119845-A1 HYDROPHILIC ANTI-FOG COATINGS Innosense LLC (US) 2017-01-25 EP claimed
US-20160168559-A1 BIOCATALYTICAL COMPOSITION INOFEA GMBH (CH) 2016-06-16 US claimed
EP-3027750-A1 BIOCATALYTICAL COMPOSITION Inofea GmbH (CH) 2016-06-08 EP claimed
US-20160010241-A1 METHOD FOR PRODUCING NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE AND NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE PRODUCED THEREBY I-SENS, INC. (KR) 2016-01-14 US claimed
US-20150344725-A1 HYDROPHILIC ANTI-FOG COATINGS KISHOLOYGOSWAMI LLC 2015-12-03 US claimed
WO-2015148312-A1 HYDROPHILIC ANTI-FOG COATINGS INNOSENSE, LLC (US) 2015-10-01 WO claimed
WO-2015014888-A1 BIOCATALYTICAL COMPOSITION INOFEA GMBH (CH) 2015-02-05 WO claimed
EP-4739337-A1 FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS COMPRISING PANCREATIC ENZYMES Perseo Pharma AG (CH) 2026-05-13 EP disclosed
EP-4739336-A2 METHOD FOR IMMOBILIZATION OF PROTEINS Perseo Pharma AG (CH) 2026-05-13 EP disclosed
EP-4739348-A1 BIOCATALYTICAL COMPOSITIONS Perseo Pharma AG (CH) 2026-05-13 EP disclosed
US-20260097103-A1 FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS PERSEO PHARMA AG (CH) 2026-04-09 US disclosed
EP-2145929-A1 Method for manufacturing redispersible, surface-modified silicon dioxide particles Evonik Degussa GmbH (DE) 2010-01-20 EP disclosed
EP-2145928-A1 Dispersion made of hydrophobic silicon dioxide particles and granulate made from same Evonik Degussa GmbH (DE) 2010-01-20 EP disclosed
US-20080216709-A1 CATIONICALLY STABILISED AQUEOUS SILICA DISPERSION, METHOD FOR ITS PRODUCTION AND ITS USE BUHLER PARTEC GMBH (DE) 2008-09-11 US disclosed
EP-1894888-A1 Cationically stabilized aqueons silica dispersions, method for manufacture and use thereof. Bühler Partec GmbH (DE) 2008-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097103-A1 FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS CTRL, PREP, ANPEP KDM4E 3283/4885MAPK1 4722/4885HIF1A 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.