SCHEMBL960689

SCHEMBL960689

CO[Si](CCCNC(C)=O)(OC)OC

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
MAPK1 P28482 1/20 0.56
HIF1A Q16665 1/20 0.56
PAOX Q6QHF9 3/20 0.47
ADRA1A P35348 1/20 0.45
MTNR1A P48039 5/20 0.42
MTNR1B P49286 5/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17457453 0.88 PAOX (0.48) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL83591 0.87 KDM4E (0.42) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL31565700 0.86 KDM4E (0.48) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL254189 0.84 EPHX1 (0.46) KDM4EMAPK1HIF1ATSHR
SCHEMBL1810892 0.83 EPHX1 (0.36) KDM4EMAPK1HIF1AADRA1ATSHR
SCHEMBL467687 0.83 EPHX1 (0.55) KDM4EMAPK1HIF1AMTNR1AMTNR1B
SCHEMBL18180992 0.83 TSHR (0.44) KDM4EMAPK1HIF1ASMN1; SMN2TSHR
SCHEMBL9322077 0.82 TSHR (0.40) KDM4EMAPK1HIF1AADRA1ASMN1; SMN2
SCHEMBL49082 0.81 MTNR1A (0.37) KDM4EMAPK1HIF1APAOXMTNR1A
SCHEMBL22174072 0.81 TSHR (0.52) KDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12469872-B2 Fluoropolymer hybrid composite SYENSQO SA (BE) 2025-11-11 US claimed
US-12391819-B2 Fluoropolymer-based hybrid organic/inorganic composites SYENSQO SA (BE) 2025-08-19 US claimed
EP-3724939-B1 FLUOROPOLYMER MEMBRANE FOR ELECTROCHEMICAL DEVICES SYENSQO SA (BE) 2025-08-13 EP claimed
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO claimed
CN-115895583-B Under-coating-free dealcoholized single-component room temperature vulcanized silicone rubber for hydrophilic aluminum foil water-resistant adhesion and preparation method thereof 广州集泰化工股份有限公司 2025-03-04 CN claimed
CN-118931455-A Thermosensitive conductive adhesive and preparation method thereof 苏州领冠新能源科技有限公司 2024-11-12 CN claimed
US-11975091-B2 Composition for enhancing protein strength LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-05-07 US claimed
CN-111466042-B Fluoropolymer membranes for electrochemical devices 索尔维公司 2024-03-29 CN claimed
US-20240094630-A1 IMPRINT COMPOSITIONS WITH PASSIVATED NANOPARTICLES AND MATERIALS AND PROCESSES FOR MAKING THE SAME APPLIED MATERIALS, INC. 2024-03-21 US claimed
CN-117701240-A Organopolysiloxane composition with good shape retention and preparation method thereof 烟台德邦科技股份有限公司 2024-03-15 CN claimed
WO-2016066610-A1 POLYMER COMPRISING ALKOXYSILANE GROUPS AND USE IN COSMETICS L'OREAL (FR) 2016-05-06 WO claimed
US-20150253317-A1 LABEL-FREE DETECTION OF RENAL CANCER WASHINGTON UNIVERSITY 2015-09-10 US claimed
WO-2015058046-A1 PLASMONIC BIOSENSORS WITH BUILT-IN ARTIFICIAL ANTIBODIES WASHINGTON UNIVERSITY (US) 2015-04-23 WO claimed
EP-2580294-B1 PVDF COATING COMPOSITIONS SOLVAY SOLEXIS SPA (IT) 2015-02-25 EP claimed
EP-2580294-A1 PVDF COATING COMPOSITIONS Solvay Solexis S.p.A. (IT) 2013-04-17 EP claimed
US-20130090417-A1 PVDF coating compositions SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2013-04-11 US claimed
WO-2011157657-A1 PVDF COATING COMPOSITIONS SOLVAY SOLEXIS S.P.A. (IT) 2011-12-22 WO claimed
US-7921911-B2 Surface-modifying agents for wettability modification SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-04-12 US claimed
WO-2010076745-A1 SURFACE-MODIFYING AGENTS FOR WETTABILITY MODIFICATION SCHLUMBERGER CANADA LIMITED (CA) 2010-07-08 WO claimed
US-20100163234-A1 Surface-Modifying Agents for Wettability Modification SCHLUMBERGER TECHNOLOGY CORPORATION 2010-07-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11975091-B2 Composition for enhancing protein strength CUTA, S100A4, S100A8 KDM4E 437/4885MAPK1 2546/4885HIF1A 3977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.