Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764115 | 0.78 | PTPN22 (0.44) | PTPN22LDHAMAPTALDH1A1NPSR1 | |
| SCHEMBL8361557 | 0.78 | — | — | |
| SCHEMBL13004790 | 0.67 | PTPN22 (0.46) | PTPN22LDHAMAPTALDH1A1NPSR1 | |
| SCHEMBL11825654 | 0.67 | ESR2 (0.41) | MAPTALDH1A1GAACYP2C9 | |
| SCHEMBL8055785 | 0.67 | CNR2 (0.36) | MAPTALDH1A1NPSR1HPGDHSD17B10 | |
| SCHEMBL8693538 | 0.66 | FAAH (0.40) | GAA | |
| SCHEMBL8359112 | 0.66 | GAA (0.36) | MAPTGAACYP1A2 | |
| SCHEMBL13004759 | 0.65 | LDHA (0.53) | LDHAMAPTHPGDKDM4E | |
| SCHEMBL15009451 | 0.64 | RCE1 (0.40) | PTPN22LDHAMAPTALDH1A1NPSR1 | |
| SCHEMBL9408536 | 0.63 | STS (0.43) | PTPN22LDHAMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856522-A | Method of using synthesis of 1,2-dioxetanes and kits therefore | TROPIX, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5777133-A | Synthesis of 1, 2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5679802-A | 1,2-dioxetanes useful in chemiluminescent immunoassays | TROPIX, INC. (US) | 1997-10-21 | — | — | US | disclosed |