Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 5/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353973 | 0.77 | MEN1 (0.56) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6431080 | 0.76 | ABCC1 (0.50) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL22525011 | 0.74 | KMT2A (0.58) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL211260 | 0.74 | KMT2A (0.61) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL13936398 | 0.74 | DHODH (0.64) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL4749159 | 0.74 | DHODH (0.69) | MASP2KMT2AMEN1PKMDHODH | |
| SCHEMBL6326283 | 0.72 | KMT2A (0.62) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL4047678 | 0.72 | NPSR1 (0.43) | KMT2AMEN1PKMALDH1A1L3MBTL1 | |
| SCHEMBL11278636 | 0.72 | ABCC1 (0.60) | ABCC1MASP2KMT2AMEN1PKM | |
| SCHEMBL20577043 | 0.72 | ABCC1 (0.63) | ABCC1MASP2KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |