SCHEMBL11278636

SCHEMBL11278636

CNC(=O)N(C)C(=O)Nc1ccccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 6/20 0.60
KMT2A Q03164 2/20 0.58
MASP2 O00187 1/20 0.58
MEN1 O00255 1/20 0.51
PKM P14618 1/20 0.51
DHODH Q02127 3/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
RBP4 P02753 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10770854 0.79 RAB9A (0.55) KMT2AMEN1POLB
SCHEMBL11260224 0.79 CYP1A2 (0.49) KMT2AMEN1
SCHEMBL11262218 0.78 MTOR (0.53) KMT2AMEN1POLB
SCHEMBL8686791 0.78 ALDH1A1 (0.70) ABCC1KMT2AMASP2MEN1PKM
SCHEMBL11259121 0.75 ALDH1A1 (0.50) KMT2AMEN1KDM4EPOLB
SCHEMBL5129490 0.75 KDM4E (0.63) ABCC1KMT2AMASP2MEN1PKM
SCHEMBL25054195 0.73 MASP2 (1.00) ABCC1KMT2AMASP2MEN1PKM
SCHEMBL110042 0.73 POLB (0.72) ABCC1KMT2AMASP2MEN1PKM
SCHEMBL29437050 0.73 POLB (0.72) ABCC1KMT2AMASP2MEN1PKM
SCHEMBL27819891 0.73 POLB (0.72) ABCC1KMT2AMASP2MEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4350700-A ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1982-09-21 US disclosed
US-4287207-A USED AS AN ANALGESIC, ANTIPYRETIC OR ANTIINFLAMMATORY AGENT TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1981-09-01 US disclosed