Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532921 | 1.00 | OPRK1 (0.34) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL9532910 | 1.00 | OPRK1 (0.34) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL2847058 | 1.00 | OPRK1 (0.34) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL2827553 | 1.00 | OPRK1 (0.34) | OPRK1NPC1RAB9AKMT2AGAA | |
| Hydrochloric Acid SCHEMBL3114222 | 0.98 | OPRK1 (0.33) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL29187947 | 0.86 | GAA (0.33) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL29936637 | 0.86 | GAA (0.33) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL20598843 | 0.86 | GAA (0.33) | OPRK1NPC1RAB9AKMT2AGAA | |
| SCHEMBL30863789 | 0.84 | CHRNB2 (0.40) | OPRK1GAA | |
| SCHEMBL18956885 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843552-A | Resolution method of cis-4-amino-3-methoxypiperidine-1-formate optical isomer | 中国医学科学院药物研究所 | 2024-04-09 | — | — | CN | claimed |
| CN-117843552-A | Resolution method of cis-4-amino-3-methoxypiperidine-1-formate optical isomer | 中国医学科学院药物研究所 | 2024-04-09 | — | — | CN | disclosed |
| EP-1853586-B1 | ANTIBACTERIAL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| EP-0669919-B1 | USE OF DIMETHYLBENZOFURANS AND DIMETHYLBENZOPYRANS AS 5-HT3 ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 1999-01-27 | — | — | EP | disclosed |
| US-5863923-A | TREATMENT OF ANXIETY, PSYCHOSIS, SCHIZOPHRENIA, DRUG ABUSE, IRRITABLE BOWEL SYNDROME | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-01-26 | — | — | US | disclosed |
| US-5674868-A | ADMINISTERING TO TREAT DISORDERS SUCH AS ANXIETY, PSYCHOSIS, DEPRESSION, SCHIZOPHRENIA, DURG ABUSE, MIGRAINE, EMESIS AND IRRITABLE BOWEL SYNDROME | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-10-07 | — | — | US | disclosed |
| EP-0251417-B1 | 4-(AROYLAMINO) PIPERIDINEBUTANAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-04-14 | — | — | EP | disclosed |