Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588243 | 0.89 | AGTR1 (0.34) | AGTR1PPARGAGTR2 | |
| SCHEMBL8363428 | 0.84 | AGTR1 (0.40) | AGTR1PPARGAGTR2 | |
| SCHEMBL8363421 | 0.84 | KDM4E (0.34) | PPARG | |
| SCHEMBL8363423 | 0.83 | AGTR1 (0.32) | AGTR1PPARGAGTR2 | |
| SCHEMBL8359564 | 0.82 | AGTR1 (0.32) | AGTR1PPARGAGTR2 | |
| SCHEMBL8364105 | 0.81 | AGTR1 (0.35) | AGTR1PPARGAGTR2 | |
| SCHEMBL8363470 | 0.81 | PDE5A (0.32) | AGTR1PPARG | |
| SCHEMBL8364598 | 0.80 | PI4KA (0.35) | AGTR1PPARGAGTR2 | |
| SCHEMBL8356866 | 0.80 | AGTR1 (0.34) | AGTR1PPARGAGTR2 | |
| SCHEMBL8359912 | 0.78 | AGTR1 (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |