Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.31 |
| ▸ | DRD5 | P21918 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359446 | 0.89 | AGTR1 (0.33) | AGTR1AGTR2PPARG | |
| SCHEMBL8356866 | 0.83 | AGTR1 (0.34) | AGTR1AGTR2PPARGDRD1DRD5 | |
| SCHEMBL8586719 | 0.81 | AGTR1 (0.35) | AGTR1AGTR2PPARG | |
| SCHEMBL8363423 | 0.80 | AGTR1 (0.32) | AGTR1AGTR2PPARG | |
| SCHEMBL8361950 | 0.79 | AGTR1 (0.38) | AGTR1AGTR2PPARG | |
| SCHEMBL8363471 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2PPARG | |
| SCHEMBL9016476 | 0.77 | ESR2 (0.36) | AGTR1AGTR2PPARG | |
| SCHEMBL8363421 | 0.72 | KDM4E (0.34) | PPARG | |
| SCHEMBL8363428 | 0.72 | AGTR1 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL8362813 | 0.71 | POLB (0.35) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |