Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680248 | 0.72 | ERN1 (0.38) | MAPTTSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL647822 | 0.71 | TDP1 (0.44) | TDP1MAPTTSHRAPEX1SMN1; SMN2 | |
| SCHEMBL11838471 | 0.68 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL4478128 | 0.67 | AHR (0.42) | TSHRNOS1CYP1A2 | |
| SCHEMBL7279169 | 0.67 | GABRA1 (0.39) | MAPTTSHRMEN1KMT2ANPC1 | |
| SCHEMBL259909 | 0.67 | TDP1 (0.54) | TDP1MAPTTSHRAPEX1SMN1; SMN2 | |
| SCHEMBL16289391 | 0.66 | TDP1 (0.45) | TDP1MAPTTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL386455 | 0.66 | TDP1 (0.61) | TDP1MAPTTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL835944 | 0.66 | MAPT (0.53) | TDP1MAPTTSHRAPEX1SMN1; SMN2 | |
| SCHEMBL3056048 | 0.65 | TRIM24 (0.57) | TDP1MAPTSMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200256858-A1 | Modifiable Chemical Inducers of Proximity and Methods of Using the Same | TAKARA BIO USA, INC. | 2020-08-13 | — | — | US | claimed |
| US-20230227889-A1 | Multiplex Preparation of Barcoded Gene Specific DNA Fragments | CELLECTA, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230054869-A1 | Methods and Compositions Employing Blocked Primers | TAKARA BIO USA, INC. | 2023-02-23 | — | — | US | disclosed |
| EP-4127221-A1 | SINGLE CELL GENETIC ANALYSIS | Cellecta, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| US-11371087-B2 | Methods and compositions employing blocked primers | TAKARA BIO USA, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-20220195493-A1 | Multiplex Preparation of Barcoded Gene Specific DNA Fragments | CELLECTA, INC. | 2022-06-23 | — | — | US | disclosed |
| US-20220145285-A1 | Compartment-Free Single Cell Genetic Analysis | CELLECTA, INC. | 2022-05-12 | — | — | US | disclosed |
| EP-3971169-A1 | METHOD FOR PRODUCING, IN A CELL, A PROTEIN OR A POLYPEPTIDE COMPRISING A TETRAZINE AMINO ACID | Oregon State University (US) | 2022-03-23 | — | — | EP | disclosed |
| US-11274334-B2 | Multiplex preparation of barcoded gene specific DNA fragments | CELLECTA, INC. (US) | 2022-03-15 | — | — | US | disclosed |
| US-20210301329-A1 | Single Cell Genetic Analysis | CELLECTA, INC. | 2021-09-30 | — | — | US | disclosed |
| EP-0004466-B1 | DEMETHYL MAYTANSINOIDS AND METHODS FOR PRODUCING THEM | Takeda Chemical Industries, Ltd. (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4307016-A | FUNGICIDES, PROTOZOACIDES OR ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
| US-4294757-A | BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4260608-A | ANTIMICROBIAL, ANTIMITOTIC, AND ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| US-4256746-A | ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1981-03-17 | — | — | US | disclosed |
| US-4248870-A | MICROBIOCIDES, ANTITUMOR AGENTS, AND ANTIMITOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-03 | — | — | US | disclosed |
| EP-0014402-A1 | Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-08-20 | — | — | EP | disclosed |
| EP-0011277-A1 | Dechloromaytansinoids, their production and use and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0010735-A1 | Maytansinoids, their production and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-05-14 | — | — | EP | disclosed |
| EP-0004466-A1 | Demethyl maytansinoids and methods for producing them | Takeda Chemical Industries, Ltd. (JP) | 1979-10-03 | — | — | EP | disclosed |