Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL28964520 | 0.89 | MAPT (0.45) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| Ethane SCHEMBL28964525 | 0.87 | MAPT (0.44) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL10463259 | 0.86 | TYMS (0.46) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL15596391 | 0.84 | ALDH1A1 (0.47) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| Ethoxycarbonyl Group SCHEMBL27476172 | 0.83 | MAPT (0.40) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL15801718 | 0.80 | ALDH1A1 (0.42) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL6537493 | 0.77 | ALDH1A1 (0.58) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL7423121 | 0.77 | ALDH1A1 (0.58) | TDP1MAPTSMN1; SMN2APEX1MEN1 | |
| SCHEMBL15796857 | 0.76 | ALDH1A1 (0.47) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| Indole SCHEMBL27976837 | 0.76 | TRPA1 (0.63) | TDP1MAPTSMN1; SMN2APEX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580174-A | Preparation method of 7-nitroindole | 武威广达科技有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-116178469-A | Oligonucleotide modified podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-05-30 | — | — | CN | claimed |
| CN-114394963-B | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2023-05-23 | — | — | CN | claimed |
| CN-110845388-A | Method for synthesizing 7-nitroindole | 江苏苏利精细化工股份有限公司 | 2020-02-28 | — | — | CN | claimed |
| US-9486892-B2 | Polishing composition | FUJIMI INCORPORATED (JP) | 2016-11-08 | — | — | US | claimed |
| EP-2486115-B1 | ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF | FRAUNHOFER GES FORSCHUNG (DE) | 2015-05-20 | — | — | EP | claimed |
| CN-103059065-B | Azo metal complex and preparation method thereof | SHANGHAI TOYOU DIGITAL TECH CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-103059598-B | Azo blue-ray optical storage dye and preparation method thereof | SHANGHAI TOYOU DIGITAL TECH CO LTD | 2014-04-02 | — | — | CN | claimed |
| CN-103059065-A | Azo metal complex and preparation method thereof | SHANGHAI TOYOU DIGITAL TECH CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-103059598-A | Azo blue-ray optical storage dye and preparation method thereof | SHANGHAI TOYOU DIGITAL TECH CO LTD | 2013-04-24 | — | — | CN | claimed |
| EP-1327632-B1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | MITSUBISHI RAYON CO (JP) | 2008-12-03 | — | — | EP | claimed |
| EP-1077699-A1 | AMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 2001-02-28 | — | — | EP | claimed |
| WO-1999059582-A1 | AMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | claimed |
| US-12630539-B2 | Amide compound, pharmaceutical composition and use thereof | ARTIVILA (SHENZHEN) INNOVATION CENTER, LTD. (CN) | 2026-05-19 | — | — | US | disclosed |
| CN-116874548-B | MDM2 double-site inhibitor and application thereof in antitumor activity | 中国医学科学院药用植物研究所 | 2026-05-15 | — | — | CN | disclosed |
| US-20260125423-A1 | PEPTIDES FOR INCRETIN SYNTHESIS | LILLY CO ELI (US) | 2026-05-07 | — | — | US | disclosed |
| US-4506078-A | 7-AMINOINDOLE PHOTOGRAPHIC DYES | HOFFMANN-LA ROCHE INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4506078-A | 7-AMINOINDOLE PHOTOGRAPHIC DYES | HOFFMANN-LA ROCHE INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-3983137-A | Process for preparing 3-(indol-3-yl)-dehydronaphthalide hydrochlorides | POLAROID CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3933854-A | CHEMICAL INTERMEDIATES FOR INDICATOR DYES | POLAROID CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630539-B2 | Amide compound, pharmaceutical composition and use thereof | JAK2, JAK1, JAK3 | TDP1 4239/4885MAPT 4013/4885SMN1; SMN2 3540/4885 |
| US-20260125423-A1 | PEPTIDES FOR INCRETIN SYNTHESIS | IAPP, GLP1R, VIP | TDP1 2549/4885MAPT 1173/4885SMN1; SMN2 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.