Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PCNA | P12004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839012 | 0.92 | LMNA (0.53) | LMNAMAP2K1POLBTDP1PIN1 | |
| SCHEMBL11299901 | 0.87 | LMNA (0.58) | LMNAMAP2K1POLBTDP1DYRK1A | |
| SCHEMBL8978118 | 0.83 | LMNA (0.44) | LMNAMAP2K1POLBTDP1TSHR | |
| SCHEMBL7772911 | 0.81 | LMNA (0.52) | LMNAMAP2K1 | |
| SCHEMBL8635724 | 0.81 | LMNA (0.52) | LMNAMAP2K1 | |
| SCHEMBL622562 | 0.80 | LMNA (0.48) | LMNAMAP2K1 | |
| SCHEMBL8635540 | 0.79 | LMNA (0.51) | LMNAMAP2K1 | |
| SCHEMBL9265234 | 0.78 | LMNA (0.50) | LMNAMAP2K1 | |
| SCHEMBL2011397 | 0.78 | LMNA (0.49) | LMNAMAP2K1 | |
| SCHEMBL3932936 | 0.77 | TPMT (0.37) | LMNAPOLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869024-A | USING A TRIODINATED PHENYL COMPOUND | BRACCO INTERNATIONAL B.V. (NL) | 1999-02-09 | — | — | US | disclosed |