Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 7/20 | 0.41 |
| ▸ | SULT1A1 | P50225 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL8361496 | 0.85 | HTT (0.49) | HTTGAAL3MBTL1MAOBDYRK1A | |
| SCHEMBL2676185 | 0.84 | HTT (0.61) | HTTGAAL3MBTL1DYRK1ACA12 | |
| Isobutane SCHEMBL8357971 | 0.82 | HTT (0.54) | HTTGAAL3MBTL1DYRK1ACA12 | |
| SCHEMBL1771426 | 0.78 | RAB9A (0.61) | HTTGAADYRK1AAPPMAPT | |
| SCHEMBL3100845 | 0.78 | NPC1 (0.56) | HTTGAADYRK1AAPPMAPT | |
| SCHEMBL8361626 | 0.78 | KMT2A (0.65) | HTTL3MBTL1CA12CA1CA2 | |
| SCHEMBL11875177 | 0.76 | NPC1 (0.54) | HTTGAADYRK1AAPPMAPT | |
| SCHEMBL11063766 | 0.76 | NPC1 (0.54) | HTTGAADYRK1AAPPMAPT | |
| SCHEMBL11067124 | 0.76 | NPC1 (0.54) | HTTGAADYRK1AAPPMAPT | |
| SCHEMBL8357946 | 0.75 | KMT2A (0.48) | CA1CA2CA4MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919807-A | ANTICHOLESTEROL AGENTS | DR. KARL THOMAE GMBH (DE) | 1999-07-06 | — | — | US | disclosed |