Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358041 | 0.88 | KMT2A (0.52) | MAPTCSNK1DCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8355856 | 0.86 | APP (0.65) | MAPTCSNK1DAPPCYP1A2CYP3A4 | |
| SCHEMBL8516569 | 0.83 | MAPT (0.44) | MAPTCSNK1DCYP1A2CYP3A4GAA | |
| SCHEMBL8361712 | 0.83 | CSNK1D (0.58) | CSNK1DAPPCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8359111 | 0.83 | CACNA1B (0.53) | MAPTCSNK1DCYP1A2 | |
| SCHEMBL11338493 | 0.82 | CYP1A2 (0.63) | MAPTAPPCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8357909 | 0.81 | MAOB (0.50) | MAPTCSNK1DAPPGAA | |
| SCHEMBL29016598 | 0.81 | EPHX2 (0.51) | MAPTCSNK1DAPPGLAGAA | |
| SCHEMBL30370207 | 0.81 | EPHX2 (0.44) | MAPTCSNK1DAPP | |
| SCHEMBL29016615 | 0.81 | EPHX2 (0.44) | MAPTCSNK1DAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919807-A | ANTICHOLESTEROL AGENTS | DR. KARL THOMAE GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |