Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635574 | 0.76 | FFAR1 (0.40) | FFAR1AKR1B1AGTR1AGTR2ALDH1A1 | |
| SCHEMBL8357464 | 0.71 | FFAR1 (0.43) | FFAR1AKR1B1AGTR2ALDH1A1KDM4E | |
| SCHEMBL7376271 | 0.71 | ALDH1A1 (0.42) | FFAR1AKR1B1AGTR1AGTR2ALDH1A1 | |
| SCHEMBL3976312 | 0.71 | ALDH1A1 (0.42) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL8476707 | 0.71 | KDM4E (0.41) | FFAR1AKR1B1ALDH1A1KDM4ETDP1 | |
| SCHEMBL3978309 | 0.70 | FFAR1 (0.43) | FFAR1AKR1B1AGTR1AGTR2ALDH1A1 | |
| SCHEMBL8359613 | 0.68 | FFAR1 (0.41) | FFAR1AKR1B1ALDH1A1KDM4EEGLN1 | |
| SCHEMBL9032730 | 0.68 | FFAR1 (0.41) | FFAR1AKR1B1ALDH1A1L3MBTL1EGLN1 | |
| SCHEMBL9025920 | 0.68 | FFAR1 (0.57) | FFAR1AKR1B1ALDH1A1EGLN1PPARG | |
| SCHEMBL18998062 | 0.67 | FFAR1 (0.45) | FFAR1AKR1B1AGTR1AGTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |