Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649405 | 0.75 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8645800 | 0.75 | CNR2 (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27475357 | 0.75 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8360558 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8351871 | 0.73 | HSD17B10 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1921261 | 0.73 | PTGER4 (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7726215 | 0.70 | NPSR1 (0.86) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22003802 | 0.70 | HTR6 (0.56) | KDM4EALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL5795918 | 0.69 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17396548 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |