Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360597 | 1.00 | NLN (0.55) | NLNKCNH2PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8360599 | 1.00 | NLN (0.55) | NLNKCNH2PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8365151 | 0.87 | HDAC8 (0.53) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8365150 | 0.87 | HDAC8 (0.53) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8365152 | 0.87 | HDAC8 (0.53) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL18522509 | 0.86 | PLAAT3 (0.58) | NLNPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8360817 | 0.86 | KCNH2 (0.50) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8360812 | 0.86 | KCNH2 (0.50) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8360814 | 0.86 | KCNH2 (0.50) | KCNH2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7859178 | 0.85 | MMP8 (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |