Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 7/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857066 | 0.89 | MMP8 (0.66) | MMP8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7850380 | 0.88 | CHRNB2 (0.58) | MMP8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8360599 | 0.85 | NLN (0.55) | MMP2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8360597 | 0.85 | NLN (0.55) | MMP2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8360596 | 0.85 | NLN (0.55) | MMP2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1244320 | 0.85 | CHRNB2 (0.55) | MMP8CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18522509 | 0.83 | PLAAT3 (0.58) | MMP1MMP3MMP2PLAAT3PLAAT5 | |
| SCHEMBL7857980 | 0.81 | LNPEP (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL1246343 | 0.81 | LNPEP (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL7857085 | 0.81 | MMP2 (0.56) | MMP8CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |