Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689403 | 0.84 | CPB2 (0.49) | CPB2HTR2AHRH1TLR2MMP2 | |
| SCHEMBL18725756 | 0.82 | CPB2 (0.60) | CPB2HTR2AHRH1TLR2MMP2 | |
| SCHEMBL18725757 | 0.82 | CPB2 (0.60) | CPB2HTR2AHRH1TLR2MMP2 | |
| SCHEMBL18742006 | 0.82 | CPB2 (0.60) | CPB2HTR2AHRH1TLR2MMP2 | |
| SCHEMBL9275432 | 0.82 | TLR2 (0.56) | TLR2 | |
| SCHEMBL8358645 | 0.82 | TLR2 (0.56) | TLR2 | |
| SCHEMBL9201253 | 0.81 | CTSD (0.45) | HTR2AHRH1 | |
| SCHEMBL9201265 | 0.81 | CTSD (0.45) | HTR2AHRH1 | |
| SCHEMBL8358585 | 0.78 | CYP2D6 (0.59) | TLR2 | |
| SCHEMBL23052583 | 0.78 | MMP1 (0.47) | CPB2TLR2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |