Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539630 | 0.83 | MIF (0.48) | MEN1KMT2AMIFMAPTL3MBTL1 | |
| SCHEMBL3837958 | 0.82 | MAPT (0.55) | SCN5ASCN9AKMT2AMAPTLMNA | |
| SCHEMBL13946510 | 0.82 | MAPT (0.55) | SCN5ASCN9AKMT2AMAPTLMNA | |
| SCHEMBL13946506 | 0.82 | MAPT (0.55) | SCN5ASCN9AKMT2AMAPTLMNA | |
| SCHEMBL5898532 | 0.81 | CES2 (0.44) | SCN5ASCN9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11033611 | 0.81 | MIF (0.43) | SCN5ASCN9AMEN1KMT2AMIF | |
| SCHEMBL8356496 | 0.81 | KCNN4 (0.55) | SCN5ASCN9AMEN1KMT2AMAPT | |
| SCHEMBL5898573 | 0.81 | OGG1 (0.41) | SCN5ASCN9AMEN1KMT2AMAPT | |
| SCHEMBL5898535 | 0.81 | SCN5A (0.46) | SCN5ASCN9AMEN1KMT2AMAPT | |
| SCHEMBL12316587 | 0.80 | SCN5A (0.75) | SCN5ASCN9AMEN1KMT2AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999041229-A1 | HALOGENATED PHENYL ALCOHOL AMIDES (LIGANDS OF GABAB RECEPTOR) HAVING AN ANTICONVULSANT ACTIVITY | CARVAJAL SANDOVAL GUILLERMO (MX) | 1999-08-19 | — | — | WO | disclosed |