Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423271 | 0.94 | LMNA (0.59) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL23620677 | 0.89 | LMNA (0.55) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL5423280 | 0.82 | POLB (0.44) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL1246220 | 0.74 | TSHR (0.96) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL11694406 | 0.74 | RAB9A (0.58) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL3707572 | 0.73 | LMNA (0.73) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL15944487 | 0.72 | CYP3A4 (0.69) | LMNAPOLBTSHRALDH1A1RAB9A | |
| Acetone SCHEMBL9417288 | 0.72 | MEN1 (0.47) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL10505583 | 0.72 | ALDH1A1 (0.61) | LMNAPOLBTSHRALDH1A1RAB9A | |
| SCHEMBL294992 | 0.72 | POLB (0.55) | LMNAPOLBTSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002491-A1 | MORPHOLINE AND TETRAHYDROPYRAN DRIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2004-01-08 | — | — | WO | disclosed |