Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.58 |
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660055 | 0.95 | HDAC3 (0.59) | SMPD1MGLLKDM4EALDH1A1HPGD | |
| SCHEMBL7335792 | 0.95 | SMPD1 (0.64) | SMPD1MGLLALDH1A1HPGDHDAC3 | |
| SCHEMBL24950547 | 0.94 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPDE4B | |
| SCHEMBL13461264 | 0.94 | SMPD1 (0.67) | SMPD1MGLLMAPTHDAC3HDAC2 | |
| SCHEMBL967401 | 0.94 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPDE4B | |
| SCHEMBL9304902 | 0.94 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPDE4B | |
| SCHEMBL5216700 | 0.94 | MGLL (0.62) | SMPD1MGLLHPGDMAPTNPC1 | |
| SCHEMBL9565566 | 0.94 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPDE4B | |
| SCHEMBL26480965 | 0.90 | MGLL (0.52) | SMPD1MGLLKDM4EALDH1A1HPGD | |
| SCHEMBL14930505 | 0.89 | SMPD1 (0.65) | SMPD1MGLLHPGDMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009094-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | OHIO UNIVERSITY (US) | 2004-01-29 | — | — | WO | disclosed |