Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360925 | 0.90 | SMPD1 (0.58) | MGLLSMPD1RAB9ANPC1MAPT | |
| SCHEMBL5216700 | 0.87 | MGLL (0.62) | MGLLSMPD1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18660055 | 0.86 | HDAC3 (0.59) | MGLLSMPD1RAB9ANPC1TSHR | |
| SCHEMBL7335792 | 0.85 | SMPD1 (0.64) | MGLLSMPD1ALDH1A1HPGDTHRA | |
| SCHEMBL24950547 | 0.84 | SMPD1 (0.67) | MGLLSMPD1ALDH1A1HPGDTHRA | |
| SCHEMBL9565566 | 0.84 | SMPD1 (0.67) | MGLLSMPD1ALDH1A1HPGDTHRA | |
| SCHEMBL13461264 | 0.84 | SMPD1 (0.67) | MGLLSMPD1MAPTGAAKMT2A | |
| SCHEMBL967401 | 0.84 | SMPD1 (0.67) | MGLLSMPD1ALDH1A1HPGDTHRA | |
| SCHEMBL9304902 | 0.84 | SMPD1 (0.67) | MGLLSMPD1ALDH1A1HPGDTHRA | |
| SCHEMBL14930505 | 0.83 | SMPD1 (0.65) | MGLLSMPD1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | SLC10A1, GYS2, CPT1A | MGLL 920/4885SMPD1 1078/4885RAB9A 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.