SCHEMBL8361809

SCHEMBL8361809

Nc1ccc(CC(O)C(=O)OC(Cc2ccc(N)cc2)C(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 4/20 0.46
PSAT1 Q9Y617 2/20 0.45
ACE P12821 1/20 0.43
PPARG P37231 14/20 0.42
PPARA Q07869 12/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323546 0.86 SLC7A5 (0.49) SRRPSAT1ACEPPARGPPARA
SCHEMBL352986 0.85 SRR (0.59) SRRACEPPARGPPARA
SCHEMBL28278431 0.85 SRR (0.59) SRRACEPPARGPPARA
SCHEMBL8953447 0.84 PPARG (0.54) SRRPSAT1ACEPPARGPPARA
SCHEMBL8953769 0.81 PPARA (0.58) PPARGPPARA
SCHEMBL8953590 0.81 ALDH1A1 (0.42) SRRPSAT1ACEPPARGPPARA
SCHEMBL8953732 0.80 MMP1 (0.48) ACE
SCHEMBL8361807 0.79 KDM6B (0.56) SRR
SCHEMBL1094106 0.79 KDM6B (0.56) SRR
SCHEMBL1094114 0.79 KDM6B (0.56) SRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856436-A Depsipeptide derivative, process for production thereof, and novel intermediate therefor FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-01-05 US disclosed
US-5514773-A PARASITICIDES, ANTHELMINTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-07 US disclosed