Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580589 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL27638766 | 0.83 | HTR1A (0.42) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL2856220 | 0.82 | GAA (0.61) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL9558198 | 0.81 | MEN1 (0.59) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL1919434 | 0.81 | MEN1 (0.73) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL5888121 | 0.80 | HSD17B10 (0.56) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL5888051 | 0.80 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| Triethylenemelamine SCHEMBL21332502 | 0.79 | HTT (0.48) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29207063 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL1270156 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816492-A | TRPV2 channel blocker and use thereof | 伊契洛夫科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119816492-A | TRPV2 channel blocker and use thereof | 伊契洛夫科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-3564253-A1 | ANTIDEPRESSANT COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-11-06 | — | — | EP | disclosed |
| EP-0810991-B1 | 1-ARYL-2-ACYLAMINO-ETHANE COMPOUNDS AND THEIR USE AS NEUROKININ ESPECIALLY NEUROKININ 1 ANTAGONISTS | NOVARTIS AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0810991-A1 | 1-ARYL-2-ACYLAMINO-ETHANE COMPOUNDS AND THEIR USE AS NEUROKININ ESPECIALLY NEUROKININ 1 ANTAGONISTS | Novartis AG (CH) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026183-A1 | 1-ARYL-2-ACYLAMINO-ETHANE COMPOUNDS AND THEIR USE AS NEUROKININ ESPECIALLY NEUROKININ 1 ANTAGONISTS | NOVARTIS AG (CH) | 1996-08-29 | — | — | WO | disclosed |