Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594941 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL5654451 | 0.83 | RAB9A (0.50) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL1581602 | 0.83 | SMN1; SMN2 (0.54) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL693670 | 0.79 | DAO (0.49) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL24685505 | 0.79 | DAO (0.46) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL8364722 | 0.78 | SMN1; SMN2 (0.62) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL3380070 | 0.77 | MAOA (0.58) | HPGDPOLBSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL1018295 | 0.76 | SMN1; SMN2 (0.59) | LMNAHPGDGLAPOLBSMN1; SMN2 | |
| SCHEMBL13162356 | 0.76 | HTT (0.54) | LMNAHPGDSMN1; SMN2ALDH1A1GFER | |
| SCHEMBL11601101 | 0.75 | ALDH1A1 (0.56) | LMNAHPGDGLAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |